BDBM50329896 CHEMBL1271980::N-(6-(4-(allyloxy)-5-chloro-6-methylpyrimidin-2-yl)pyridin-3-yl)-2-chloroacetamide

SMILES: Cc1nc(nc(OCC=C)c1Cl)-c1ccc(NC(=O)CCl)cn1

InChI Key: InChIKey=ZVRKETNVMFVIJP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329896 (CHEMBL1271980 | N-(6-(4-(allyloxy)-5-chloro-6-meth...) Show SMILES Cc1nc(nc(OCC=C)c1Cl)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C15H14Cl2N4O2/c1-3-6-23-15-13(17)9(2)19-14(21-15)11-5-4-10(8-18-11)20-12(22)7-16/h3-5,8H,1,6-7H2,2H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329896 (CHEMBL1271980 | N-(6-(4-(allyloxy)-5-chloro-6-meth...) Show SMILES Cc1nc(nc(OCC=C)c1Cl)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C15H14Cl2N4O2/c1-3-6-23-15-13(17)9(2)19-14(21-15)11-5-4-10(8-18-11)20-12(22)7-16/h3-5,8H,1,6-7H2,2H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair