BDBM50329960 (3-(2-(1,3,4-oxadiazol-2-yl)propan-2-yl)-6-chloro-5-methyl-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl)((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)methanone::CHEMBL1269568

SMILES: Cc1cc2C(CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)c1nnco1

InChI Key: InChIKey=OJUNTGQGOBJANH-QDSWCARHSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50329960 ((3-(2-(1,3,4-oxadiazol-2-yl)propan-2-yl)-6-chloro-...) Show SMILES Cc1cc2C(CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)c1nnco1 |r| Show InChI InChI=1S/C34H41ClF2N4O2/c1-20-13-23-26(15-28(20)35)34(16-27(23)33(5,6)31-39-38-19-43-31)9-11-40(12-10-34)30(42)25-18-41(32(2,3)4)17-24(25)22-8-7-21(36)14-29(22)37/h7-8,13-15,19,24-25,27H,9-12,16-18H2,1-6H3/t24-,25+,27?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	211	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human MC4 receptor				Bioorg Med Chem Lett 20: 6524-32 (2010) Article DOI: 10.1016/j.bmcl.2010.09.049 BindingDB Entry DOI: 10.7270/Q24M94SF
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50329960 ((3-(2-(1,3,4-oxadiazol-2-yl)propan-2-yl)-6-chloro-...) Show SMILES Cc1cc2C(CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)c1nnco1 |r| Show InChI InChI=1S/C34H41ClF2N4O2/c1-20-13-23-26(15-28(20)35)34(16-27(23)33(5,6)31-39-38-19-43-31)9-11-40(12-10-34)30(42)25-18-41(32(2,3)4)17-24(25)22-8-7-21(36)14-29(22)37/h7-8,13-15,19,24-25,27H,9-12,16-18H2,1-6H3/t24-,25+,27?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MC4 receptor				Bioorg Med Chem Lett 20: 6524-32 (2010) Article DOI: 10.1016/j.bmcl.2010.09.049 BindingDB Entry DOI: 10.7270/Q24M94SF
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50329960 ((3-(2-(1,3,4-oxadiazol-2-yl)propan-2-yl)-6-chloro-...) Show SMILES Cc1cc2C(CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)c1nnco1 |r| Show InChI InChI=1S/C34H41ClF2N4O2/c1-20-13-23-26(15-28(20)35)34(16-27(23)33(5,6)31-39-38-19-43-31)9-11-40(12-10-34)30(42)25-18-41(32(2,3)4)17-24(25)22-8-7-21(36)14-29(22)37/h7-8,13-15,19,24-25,27H,9-12,16-18H2,1-6H3/t24-,25+,27?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MC4 receptor				Bioorg Med Chem Lett 20: 6524-32 (2010) Article DOI: 10.1016/j.bmcl.2010.09.049 BindingDB Entry DOI: 10.7270/Q24M94SF
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50329960 ((3-(2-(1,3,4-oxadiazol-2-yl)propan-2-yl)-6-chloro-...) Show SMILES Cc1cc2C(CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)c1nnco1 |r| Show InChI InChI=1S/C34H41ClF2N4O2/c1-20-13-23-26(15-28(20)35)34(16-27(23)33(5,6)31-39-38-19-43-31)9-11-40(12-10-34)30(42)25-18-41(32(2,3)4)17-24(25)22-8-7-21(36)14-29(22)37/h7-8,13-15,19,24-25,27H,9-12,16-18H2,1-6H3/t24-,25+,27?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human MC4 receptor				Bioorg Med Chem Lett 20: 6524-32 (2010) Article DOI: 10.1016/j.bmcl.2010.09.049 BindingDB Entry DOI: 10.7270/Q24M94SF
					More data for this Ligand-Target Pair