null

SMILES: CC(C)c1[nH]ncc1-c1nc(NC2CCN(C)CC2)ncc1C

InChI Key: InChIKey=DEQNZPVZBGIKEZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50330270 (CHEMBL1271509 | [4-(3-Isopropyl-1H-pyrazol-4-yl)-5...) Show SMILES CC(C)c1[nH]ncc1-c1nc(NC2CCN(C)CC2)ncc1C Show InChI InChI=1S/C17H26N6/c1-11(2)15-14(10-19-22-15)16-12(3)9-18-17(21-16)20-13-5-7-23(4)8-6-13/h9-11,13H,5-8H2,1-4H3,(H,19,22)(H,18,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A after 2 hrs by IMAP-FP assay				J Med Chem 53: 7938-57 (2010) Article DOI: 10.1021/jm100571n BindingDB Entry DOI: 10.7270/Q2T72HQV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50330270 (CHEMBL1271509 | [4-(3-Isopropyl-1H-pyrazol-4-yl)-5...) Show SMILES CC(C)c1[nH]ncc1-c1nc(NC2CCN(C)CC2)ncc1C Show InChI InChI=1S/C17H26N6/c1-11(2)15-14(10-19-22-15)16-12(3)9-18-17(21-16)20-13-5-7-23(4)8-6-13/h9-11,13H,5-8H2,1-4H3,(H,19,22)(H,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human CDK1/cyclin B after 2 hrs by IMAP-FP assay				J Med Chem 53: 7938-57 (2010) Article DOI: 10.1021/jm100571n BindingDB Entry DOI: 10.7270/Q2T72HQV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM50330270 (CHEMBL1271509 | [4-(3-Isopropyl-1H-pyrazol-4-yl)-5...) Show SMILES CC(C)c1[nH]ncc1-c1nc(NC2CCN(C)CC2)ncc1C Show InChI InChI=1S/C17H26N6/c1-11(2)15-14(10-19-22-15)16-12(3)9-18-17(21-16)20-13-5-7-23(4)8-6-13/h9-11,13H,5-8H2,1-4H3,(H,19,22)(H,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human CDK4/cyclin D1 expressed in baculovirus infected Sf21 cells after 60 mins by TR-FRET assay				J Med Chem 53: 7938-57 (2010) Article DOI: 10.1021/jm100571n BindingDB Entry DOI: 10.7270/Q2T72HQV
					More data for this Ligand-Target Pair