BDBM50330362 (1R,5S)-N-cyclopropyl-N-((2-methoxy-3-methylpyridin-4-yl)methyl)-7-(4-(3-(2-methoxybenzyloxy)propoxy)phenyl)-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide::CHEMBL1276274

SMILES: COc1ccccc1COCCCOc1ccc(cc1)C1=C([C@H]2CNC[C@@H](C1)N2)C(=O)N(Cc1ccnc(OC)c1C)C1CC1

InChI Key: InChIKey=VDYBDHDHYNXGPG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50330362 ((1R,5S)-N-cyclopropyl-N-((2-methoxy-3-methylpyridi...) Show SMILES COc1ccccc1COCCCOc1ccc(cc1)C1=C([C@H]2CNC[C@@H](C1)N2)C(=O)N(Cc1ccnc(OC)c1C)C1CC1 |r,t:22| Show InChI InChI=1S/C36H44N4O5/c1-24-26(15-16-38-35(24)43-3)22-40(29-11-12-29)36(41)34-31(19-28-20-37-21-32(34)39-28)25-9-13-30(14-10-25)45-18-6-17-44-23-27-7-4-5-8-33(27)42-2/h4-5,7-10,13-16,28-29,32,37,39H,6,11-12,17-23H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals Corp Curated by ChEMBL					Assay Description Inhibition of renin in plasma				J Med Chem 53: 7490-520 (2010) Article DOI: 10.1021/jm901885s BindingDB Entry DOI: 10.7270/Q2S75GKG
					More data for this Ligand-Target Pair
Renin (Homo sapiens (Human))	BDBM50330362 ((1R,5S)-N-cyclopropyl-N-((2-methoxy-3-methylpyridi...) Show SMILES COc1ccccc1COCCCOc1ccc(cc1)C1=C([C@H]2CNC[C@@H](C1)N2)C(=O)N(Cc1ccnc(OC)c1C)C1CC1 |r,t:22| Show InChI InChI=1S/C36H44N4O5/c1-24-26(15-16-38-35(24)43-3)22-40(29-11-12-29)36(41)34-31(19-28-20-37-21-32(34)39-28)25-9-13-30(14-10-25)45-18-6-17-44-23-27-7-4-5-8-33(27)42-2/h4-5,7-10,13-16,28-29,32,37,39H,6,11-12,17-23H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals Corp Curated by ChEMBL					Assay Description Inhibition of human recombinant renin in buffer				J Med Chem 53: 7490-520 (2010) Article DOI: 10.1021/jm901885s BindingDB Entry DOI: 10.7270/Q2S75GKG
					More data for this Ligand-Target Pair