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BDBM50330389 3-((2-(l-Prolinol)-1-yl)-ethyl)uracil::CHEMBL1275721

SMILES: OC[C@@H]1CCCN1CCn1c(=O)cc[nH]c1=O

InChI Key: InChIKey=ZTYNAVOYGKTLKL-VIFPVBQESA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330389   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Purine Nucleoside Phosphorylase (PNP)


(Plasmodium falciparum)
BDBM50330389
PNG
(3-((2-(l-Prolinol)-1-yl)-ethyl)uracil | CHEMBL1275...)
Show SMILES OC[C@@H]1CCCN1CCn1c(=O)cc[nH]c1=O |r|
Show InChI InChI=1S/C11H17N3O3/c15-8-9-2-1-5-13(9)6-7-14-10(16)3-4-12-11(14)17/h3-4,9,15H,1-2,5-8H2,(H,12,17)/t9-/m0/s1
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
7.50E+4n/an/an/an/an/an/an/an/a



Instituto de Parasitología y Biomedicina López-Neyra

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometry


Eur J Med Chem 45: 5140-9 (2010)


Article DOI: 10.1016/j.ejmech.2010.08.026
BindingDB Entry DOI: 10.7270/Q24J0FB7
More data for this
Ligand-Target Pair
Purine Nucleoside Phosphorylase (PNP)


(Plasmodium falciparum)
BDBM50330389
PNG
(3-((2-(l-Prolinol)-1-yl)-ethyl)uracil | CHEMBL1275...)
Show SMILES OC[C@@H]1CCCN1CCn1c(=O)cc[nH]c1=O |r|
Show InChI InChI=1S/C11H17N3O3/c15-8-9-2-1-5-13(9)6-7-14-10(16)3-4-12-11(14)17/h3-4,9,15H,1-2,5-8H2,(H,12,17)/t9-/m0/s1
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.66E+5n/an/an/an/an/an/a



Instituto de Parasitología y Biomedicina López-Neyra

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometry


Eur J Med Chem 45: 5140-9 (2010)


Article DOI: 10.1016/j.ejmech.2010.08.026
BindingDB Entry DOI: 10.7270/Q24J0FB7
More data for this
Ligand-Target Pair