BDBM50330393 5-benzylpyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL1275661

SMILES: Oc1[nH]c(=O)[nH]c(=O)c1Cc1ccccc1

InChI Key: InChIKey=XWSCPQLXAUJYEY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine Nucleoside Phosphorylase (PNP) (Plasmodium falciparum)	BDBM50330393 (5-benzylpyrimidine-2,4,6(1H,3H,5H)-trione | CHEMBL...) Show SMILES Oc1[nH]c(=O)[nH]c(=O)c1Cc1ccccc1 Show InChI InChI=1S/C11H10N2O3/c14-9-8(10(15)13-11(16)12-9)6-7-4-2-1-3-5-7/h1-5H,6H2,(H3,12,13,14,15,16)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Parasitología y Biomedicina López-Neyra Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometry				Eur J Med Chem 45: 5140-9 (2010) Article DOI: 10.1016/j.ejmech.2010.08.026 BindingDB Entry DOI: 10.7270/Q24J0FB7
					More data for this Ligand-Target Pair