BDBM50330394 1-((2-Pyrrolidine-1-yl)-ethyl)uracil::CHEMBL1275699

SMILES: O=c1ccn(CCN2CCCC2)c(=O)[nH]1

InChI Key: InChIKey=WKIGBLAGQCDFDW-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine Nucleoside Phosphorylase (PNP) (Plasmodium falciparum)	BDBM50330394 (1-((2-Pyrrolidine-1-yl)-ethyl)uracil | CHEMBL12756...) Show SMILES O=c1ccn(CCN2CCCC2)c(=O)[nH]1 Show InChI InChI=1S/C10H15N3O2/c14-9-3-6-13(10(15)11-9)8-7-12-4-1-2-5-12/h3,6H,1-2,4-5,7-8H2,(H,11,14,15)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Parasitología y Biomedicina López-Neyra Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometry				Eur J Med Chem 45: 5140-9 (2010) Article DOI: 10.1016/j.ejmech.2010.08.026 BindingDB Entry DOI: 10.7270/Q24J0FB7
					More data for this Ligand-Target Pair
Purine Nucleoside Phosphorylase (PNP) (Plasmodium falciparum)	BDBM50330394 (1-((2-Pyrrolidine-1-yl)-ethyl)uracil | CHEMBL12756...) Show SMILES O=c1ccn(CCN2CCCC2)c(=O)[nH]1 Show InChI InChI=1S/C10H15N3O2/c14-9-3-6-13(10(15)11-9)8-7-12-4-1-2-5-12/h3,6H,1-2,4-5,7-8H2,(H,11,14,15)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+5	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Parasitología y Biomedicina López-Neyra Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometry				Eur J Med Chem 45: 5140-9 (2010) Article DOI: 10.1016/j.ejmech.2010.08.026 BindingDB Entry DOI: 10.7270/Q24J0FB7
					More data for this Ligand-Target Pair