BDBM50330442 3-Amino-2-[4-[4-(3-methylquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one::CHEMBL1277100

SMILES: Cc1cc2ccccc2nc1N1CCN(CCCCc2nc3CCCCc3c(=O)n2N)CC1

InChI Key: InChIKey=LZVLTVPNYIRFTB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50330442 (3-Amino-2-[4-[4-(3-methylquinolin-2-yl)piperazin-1...) Show SMILES Cc1cc2ccccc2nc1N1CCN(CCCCc2nc3CCCCc3c(=O)n2N)CC1 Show InChI InChI=1S/C26H34N6O/c1-19-18-20-8-2-4-10-22(20)29-25(19)31-16-14-30(15-17-31)13-7-6-12-24-28-23-11-5-3-9-21(23)26(33)32(24)27/h2,4,8,10,18H,3,5-7,9,11-17,27H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
ASKA Pharmaceutical Co, Ltd Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 53: 7549-63 (2010) Article DOI: 10.1021/jm1002292 BindingDB Entry DOI: 10.7270/Q27082D1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50330442 (3-Amino-2-[4-[4-(3-methylquinolin-2-yl)piperazin-1...) Show SMILES Cc1cc2ccccc2nc1N1CCN(CCCCc2nc3CCCCc3c(=O)n2N)CC1 Show InChI InChI=1S/C26H34N6O/c1-19-18-20-8-2-4-10-22(20)29-25(19)31-16-14-30(15-17-31)13-7-6-12-24-28-23-11-5-3-9-21(23)26(33)32(24)27/h2,4,8,10,18H,3,5-7,9,11-17,27H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
ASKA Pharmaceutical Co, Ltd Curated by ChEMBL					Assay Description Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 7549-63 (2010) Article DOI: 10.1021/jm1002292 BindingDB Entry DOI: 10.7270/Q27082D1
					More data for this Ligand-Target Pair