BDBM50330478 3-Amino-8-chloro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one::CHEMBL1277914

SMILES: Nn1c(CCCCN2CCN(CC2)c2ccc3ccccc3n2)nc2c(Cl)cccc2c1=O

InChI Key: InChIKey=XVBPOYYIPRSULQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50330478 (3-Amino-8-chloro-2-[4-(4-quinolin-2-ylpiperazin-1-...) Show SMILES Nn1c(CCCCN2CCN(CC2)c2ccc3ccccc3n2)nc2c(Cl)cccc2c1=O Show InChI InChI=1S/C25H27ClN6O/c26-20-8-5-7-19-24(20)29-23(32(27)25(19)33)10-3-4-13-30-14-16-31(17-15-30)22-12-11-18-6-1-2-9-21(18)28-22/h1-2,5-9,11-12H,3-4,10,13-17,27H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83.1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA Pharmaceutical Co, Ltd Curated by ChEMBL					Assay Description Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 7549-63 (2010) Article DOI: 10.1021/jm1002292 BindingDB Entry DOI: 10.7270/Q27082D1
					More data for this Ligand-Target Pair