BDBM50330505 3-(3-Methoxyphenylsulfonyl)-5-(4-methylpiperazin-1-yl)-1Hindazole::CHEMBL1276838

SMILES: COc1cccc(c1)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCN(C)CC1

InChI Key: InChIKey=OLFDZZDPXPOJLO-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330505 (3-(3-Methoxyphenylsulfonyl)-5-(4-methylpiperazin-1...) Show SMILES COc1cccc(c1)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCN(C)CC1 Show InChI InChI=1S/C19H22N4O3S/c1-22-8-10-23(11-9-22)14-6-7-18-17(12-14)19(21-20-18)27(24,25)16-5-3-4-15(13-16)26-2/h3-7,12-13H,8-11H2,1-2H3,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330505 (3-(3-Methoxyphenylsulfonyl)-5-(4-methylpiperazin-1...) Show SMILES COc1cccc(c1)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCN(C)CC1 Show InChI InChI=1S/C19H22N4O3S/c1-22-8-10-23(11-9-22)14-6-7-18-17(12-14)19(21-20-18)27(24,25)16-5-3-4-15(13-16)26-2/h3-7,12-13H,8-11H2,1-2H3,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assay				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair