BDBM50330519 5-(4-methylpiperazin-1-yl)-3-(naphthalen-1-ylsulfonyl)-1-propyl-1H-indazole::CHEMBL1277751

SMILES: CCCn1nc(c2cc(ccc12)N1CCN(C)CC1)S(=O)(=O)c1cccc2ccccc12

InChI Key: InChIKey=GDOIJRCWWFUDGD-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330519 (5-(4-methylpiperazin-1-yl)-3-(naphthalen-1-ylsulfo...) Show SMILES CCCn1nc(c2cc(ccc12)N1CCN(C)CC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C25H28N4O2S/c1-3-13-29-23-12-11-20(28-16-14-27(2)15-17-28)18-22(23)25(26-29)32(30,31)24-10-6-8-19-7-4-5-9-21(19)24/h4-12,18H,3,13-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330519 (5-(4-methylpiperazin-1-yl)-3-(naphthalen-1-ylsulfo...) Show SMILES CCCn1nc(c2cc(ccc12)N1CCN(C)CC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C25H28N4O2S/c1-3-13-29-23-12-11-20(28-16-14-27(2)15-17-28)18-22(23)25(26-29)32(30,31)24-10-6-8-19-7-4-5-9-21(19)24/h4-12,18H,3,13-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assay				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair