BDBM50330520 3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1-propyl-1H-indazole::CHEMBL1277752

SMILES: CCCn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12

InChI Key: InChIKey=RQMUCGKCHQVFCE-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330520 (3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1-p...) Show SMILES CCCn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C24H26N4O2S/c1-2-14-28-22-11-10-19(27-15-12-25-13-16-27)17-21(22)24(26-28)31(29,30)23-9-5-7-18-6-3-4-8-20(18)23/h3-11,17,25H,2,12-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330520 (3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1-p...) Show SMILES CCCn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C24H26N4O2S/c1-2-14-28-22-11-10-19(27-15-12-25-13-16-27)17-21(22)24(26-28)31(29,30)23-9-5-7-18-6-3-4-8-20(18)23/h3-11,17,25H,2,12-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assay				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair