BDBM50330926 2-[(p-Chlorophenylthio)propylide-1-enehydrazinyl]-5-methylthiazolidin-4-one::CHEMBL1276253

SMILES: Cc1sc(N=NCCCSc2ccc(Cl)cc2)nc1O

InChI Key: InChIKey=ZKVVWNNTYZCGMS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cruzipain (Trypanosoma cruzi)	BDBM50330926 (2-[(p-Chlorophenylthio)propylide-1-enehydrazinyl]-...) Show SMILES Cc1sc(N=NCCCSc2ccc(Cl)cc2)nc1O |w:4.3| Show InChI InChI=1S/C13H14ClN3OS2/c1-9-12(18)16-13(20-9)17-15-7-2-8-19-11-5-3-10(14)4-6-11/h3-6,18H,2,7-8H2,1H3	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Pernambuco Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 mins				Bioorg Med Chem 18: 7826-35 (2010) Article DOI: 10.1016/j.bmc.2010.09.056 BindingDB Entry DOI: 10.7270/Q2CV4J17
					More data for this Ligand-Target Pair