BDBM50330998 (5-(2-fluoro-3-hydroxyphenyl)thiophen-2-yl)(3-hydroxyphenyl)methanone::CHEMBL1277617

SMILES: Oc1cccc(c1)C(=O)c1ccc(s1)-c1cccc(O)c1F

InChI Key: InChIKey=RDAJIOLTWQMUSV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estradiol 17-beta-dehydrogenase 2 (Homo sapiens (Human))	BDBM50330998 ((5-(2-fluoro-3-hydroxyphenyl)thiophen-2-yl)(3-hydr...) Show SMILES Oc1cccc(c1)C(=O)c1ccc(s1)-c1cccc(O)c1F Show InChI InChI=1S/C17H11FO3S/c18-16-12(5-2-6-13(16)20)14-7-8-15(22-14)17(21)10-3-1-4-11(19)9-10/h1-9,19-20H	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 mins				J Med Chem 53: 8176-86 (2010) Article DOI: 10.1021/jm101073q BindingDB Entry DOI: 10.7270/Q2R49R0B
					More data for this Ligand-Target Pair
Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1) (Homo sapiens (Human))	BDBM50330998 ((5-(2-fluoro-3-hydroxyphenyl)thiophen-2-yl)(3-hydr...) Show SMILES Oc1cccc(c1)C(=O)c1ccc(s1)-c1cccc(O)c1F Show InChI InChI=1S/C17H11FO3S/c18-16-12(5-2-6-13(16)20)14-7-8-15(22-14)17(21)10-3-1-4-11(19)9-10/h1-9,19-20H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 mins				J Med Chem 53: 8176-86 (2010) Article DOI: 10.1021/jm101073q BindingDB Entry DOI: 10.7270/Q2R49R0B
					More data for this Ligand-Target Pair