BDBM50331008 1-(1-benzyl-3-methylpiperidin-4-yl)indolin-2-one::CHEMBL1277886

SMILES: CC1CN(Cc2ccccc2)CCC1N1C(=O)Cc2ccccc12

InChI Key: InChIKey=LQMJWHNITHLMNQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50331008 (1-(1-benzyl-3-methylpiperidin-4-yl)indolin-2-one |...) Show SMILES CC1CN(Cc2ccccc2)CCC1N1C(=O)Cc2ccccc12 Show InChI InChI=1S/C21H24N2O/c1-16-14-22(15-17-7-3-2-4-8-17)12-11-19(16)23-20-10-6-5-9-18(20)13-21(23)24/h2-10,16,19H,11-15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK292 cells after 3 hrs				J Med Chem 53: 8187-91 (2010) Article DOI: 10.1021/jm1006148 BindingDB Entry DOI: 10.7270/Q2MC9080
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor Alpha-3/Beta-4 (Rattus norvegicus (Rat))	BDBM50331008 (1-(1-benzyl-3-methylpiperidin-4-yl)indolin-2-one |...) Show SMILES CC1CN(Cc2ccccc2)CCC1N1C(=O)Cc2ccccc12 Show InChI InChI=1S/C21H24N2O/c1-16-14-22(15-17-7-3-2-4-8-17)12-11-19(16)23-20-10-6-5-9-18(20)13-21(23)24/h2-10,16,19H,11-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK292 cells after 3 hrs				J Med Chem 53: 8187-91 (2010) Article DOI: 10.1021/jm1006148 BindingDB Entry DOI: 10.7270/Q2MC9080
					More data for this Ligand-Target Pair