BDBM50331083 CHEMBL1290362::ethyl 2-(3-methyl-7-(3-methylbenzyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylthio)acetate
SMILES: CCOC(=O)CSc1nc2n(C)c(=O)[nH]c(=O)c2n1Cc1cccc(C)c1
InChI Key: InChIKey=SYESQKTWQZBHMJ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50331083 (CHEMBL1290362 | ethyl 2-(3-methyl-7-(3-methylbenzy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Konkuk University Curated by ChEMBL | Assay Description Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assay | Eur J Med Chem 45: 5420-7 (2010) Article DOI: 10.1016/j.ejmech.2010.09.002 BindingDB Entry DOI: 10.7270/Q2TX3FMZ | |||||||||||
More data for this Ligand-Target Pair |