BDBM50331087 CHEMBL1290137::N3,N5-bis(4-ethoxyphenyl)-1,2,4-triazine-3,5-diamine

SMILES: CCOc1ccc(Nc2cnnc(Nc3ccc(OCC)cc3)n2)cc1

InChI Key: InChIKey=XSGUMQQIDJGCHO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331087 (CHEMBL1290137 | N3,N5-bis(4-ethoxyphenyl)-1,2,4-tr...) Show SMILES CCOc1ccc(Nc2cnnc(Nc3ccc(OCC)cc3)n2)cc1 Show InChI InChI=1S/C19H21N5O2/c1-3-25-16-9-5-14(6-10-16)21-18-13-20-24-19(23-18)22-15-7-11-17(12-8-15)26-4-2/h5-13H,3-4H2,1-2H3,(H2,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Konkuk University Curated by ChEMBL					Assay Description Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assay				Eur J Med Chem 45: 5420-7 (2010) Article DOI: 10.1016/j.ejmech.2010.09.002 BindingDB Entry DOI: 10.7270/Q2TX3FMZ
					More data for this Ligand-Target Pair