BDBM50331260 3-(7-methoxy-1H-indol-2-yl)-1H-indazole::CHEMBL1289006

SMILES: COc1cccc2cc([nH]c12)-c1n[nH]c2ccccc12

InChI Key: InChIKey=KKUQWLWJTVFBTL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331260 (3-(7-methoxy-1H-indol-2-yl)-1H-indazole | CHEMBL12...) Show SMILES COc1cccc2cc([nH]c12)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C16H13N3O/c1-20-14-8-4-5-10-9-13(17-15(10)14)16-11-6-2-3-7-12(11)18-19-16/h2-9,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair