BDBM50331272 6-fluoro-3-(6-methyl-1H-indol-2-yl)-1H-indazole::CHEMBL1288551

SMILES: Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cc(F)ccc12

InChI Key: InChIKey=ZPUKUFGKJJXULG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331272 (6-fluoro-3-(6-methyl-1H-indol-2-yl)-1H-indazole | ...) Show SMILES Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cc(F)ccc12 Show InChI InChI=1S/C16H12FN3/c1-9-2-3-10-7-15(18-13(10)6-9)16-12-5-4-11(17)8-14(12)19-20-16/h2-8,18H,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair