BDBM50331275 3-(1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyridine::CHEMBL1288552

SMILES: c1c([nH]c2ccccc12)-c1n[nH]c2cccnc12

InChI Key: InChIKey=DMCCIGLSUATEMD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331275   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331275 (3-(1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyridine | CHE...) Show SMILES c1c([nH]c2ccccc12)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C14H10N4/c1-2-5-10-9(4-1)8-12(16-10)14-13-11(17-18-14)6-3-7-15-13/h1-8,16H,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair