BDBM50331297 (+/-)-7-Benzyloxy-3-[3-(phenysulfonyl)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol::CHEMBL1290160

SMILES: OC1CN(CCCS(=O)(=O)c2ccccc2)CCc2cc(OCc3ccccc3)ccc12

InChI Key: InChIKey=RXYNBVIFAUSQCS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50331297 ((+/-)-7-Benzyloxy-3-[3-(phenysulfonyl)propyl]-2,3,...) Show SMILES OC1CN(CCCS(=O)(=O)c2ccccc2)CCc2cc(OCc3ccccc3)ccc12 Show InChI InChI=1S/C26H29NO4S/c28-26-19-27(15-7-17-32(29,30)24-10-5-2-6-11-24)16-14-22-18-23(12-13-25(22)26)31-20-21-8-3-1-4-9-21/h1-6,8-13,18,26,28H,7,14-17,19-20H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50331297 ((+/-)-7-Benzyloxy-3-[3-(phenysulfonyl)propyl]-2,3,...) Show SMILES OC1CN(CCCS(=O)(=O)c2ccccc2)CCc2cc(OCc3ccccc3)ccc12 Show InChI InChI=1S/C26H29NO4S/c28-26-19-27(15-7-17-32(29,30)24-10-5-2-6-11-24)16-14-22-18-23(12-13-25(22)26)31-20-21-8-3-1-4-9-21/h1-6,8-13,18,26,28H,7,14-17,19-20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	349	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor guinea pig brain after 180 mins scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair