BDBM50331300 (+/-)-7-(Benzyloxy)-3-{3-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]propyl)-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol::CHEMBL1290496

SMILES: CC1(C)COC(CCCN2CCc3cc(OCc4ccccc4)ccc3C(O)C2)(OC1)c1ccc(F)cc1

InChI Key: InChIKey=KGQQZJWWWKYPSC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331300   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50331300 ((+/-)-7-(Benzyloxy)-3-{3-[2-(4-fluorophenyl)-5,5-d...) Show SMILES CC1(C)COC(CCCN2CCc3cc(OCc4ccccc4)ccc3C(O)C2)(OC1)c1ccc(F)cc1 Show InChI InChI=1S/C32H38FNO4/c1-31(2)22-37-32(38-23-31,26-9-11-27(33)12-10-26)16-6-17-34-18-15-25-19-28(13-14-29(25)30(35)20-34)36-21-24-7-4-3-5-8-24/h3-5,7-14,19,30,35H,6,15-18,20-23H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor guinea pig brain after 180 mins scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50331300 ((+/-)-7-(Benzyloxy)-3-{3-[2-(4-fluorophenyl)-5,5-d...) Show SMILES CC1(C)COC(CCCN2CCc3cc(OCc4ccccc4)ccc3C(O)C2)(OC1)c1ccc(F)cc1 Show InChI InChI=1S/C32H38FNO4/c1-31(2)22-37-32(38-23-31,26-9-11-27(33)12-10-26)16-6-17-34-18-15-25-19-28(13-14-29(25)30(35)20-34)36-21-24-7-4-3-5-8-24/h3-5,7-14,19,30,35H,6,15-18,20-23H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair