BDBM50331303 (+/-)-7-Benzyloxy-3-(1,4-dioxaspiro[4.5]decan-8-yl)-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol::CHEMBL1290607

SMILES: OC1CN(CCc2cc(OCc3ccccc3)ccc12)C1CCC2(CC1)OCCO2

InChI Key: InChIKey=GFHXCYICQJUPOX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50331303 ((+/-)-7-Benzyloxy-3-(1,4-dioxaspiro[4.5]decan-8-yl...) Show SMILES OC1CN(CCc2cc(OCc3ccccc3)ccc12)C1CCC2(CC1)OCCO2 Show InChI InChI=1S/C25H31NO4/c27-24-17-26(21-8-11-25(12-9-21)29-14-15-30-25)13-10-20-16-22(6-7-23(20)24)28-18-19-4-2-1-3-5-19/h1-7,16,21,24,27H,8-15,17-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	183	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor guinea pig brain after 180 mins scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50331303 ((+/-)-7-Benzyloxy-3-(1,4-dioxaspiro[4.5]decan-8-yl...) Show SMILES OC1CN(CCc2cc(OCc3ccccc3)ccc12)C1CCC2(CC1)OCCO2 Show InChI InChI=1S/C25H31NO4/c27-24-17-26(21-8-11-25(12-9-21)29-14-15-30-25)13-10-20-16-22(6-7-23(20)24)28-18-19-4-2-1-3-5-19/h1-7,16,21,24,27H,8-15,17-18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair