BDBM50331310 (+/-)-4-(7-Benzyloxy-1-hydroxy-2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl)-1-(4-methoxyphenyl)butan-1-one::CHEMBL1289287

SMILES: COc1ccc(cc1)C(=O)CCCN1CCc2cc(OCc3ccccc3)ccc2C(O)C1

InChI Key: InChIKey=OYLYZHZQJGNNIP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50331310 ((+/-)-4-(7-Benzyloxy-1-hydroxy-2,3,4,5-tetrahydro-...) Show SMILES COc1ccc(cc1)C(=O)CCCN1CCc2cc(OCc3ccccc3)ccc2C(O)C1 Show InChI InChI=1S/C28H31NO4/c1-32-24-11-9-22(10-12-24)27(30)8-5-16-29-17-15-23-18-25(13-14-26(23)28(31)19-29)33-20-21-6-3-2-4-7-21/h2-4,6-7,9-14,18,28,31H,5,8,15-17,19-20H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50331310 ((+/-)-4-(7-Benzyloxy-1-hydroxy-2,3,4,5-tetrahydro-...) Show SMILES COc1ccc(cc1)C(=O)CCCN1CCc2cc(OCc3ccccc3)ccc2C(O)C1 Show InChI InChI=1S/C28H31NO4/c1-32-24-11-9-22(10-12-24)27(30)8-5-16-29-17-15-23-18-25(13-14-26(23)28(31)19-29)33-20-21-6-3-2-4-7-21/h2-4,6-7,9-14,18,28,31H,5,8,15-17,19-20H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor guinea pig brain after 180 mins scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair