BDBM50331319 (+/-)-4-(1,7-Dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl)-1-(4-fluorophenyl)butan-1-one::CHEMBL1289955

SMILES: OC1CN(CCCC(=O)c2ccc(F)cc2)CCc2cc(O)ccc12

InChI Key: InChIKey=LEBXQVNFNPRKSC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331319   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50331319 ((+/-)-4-(1,7-Dihydroxy-2,3,4,5-tetrahydro-1H-3-ben...) Show SMILES OC1CN(CCCC(=O)c2ccc(F)cc2)CCc2cc(O)ccc12 Show InChI InChI=1S/C20H22FNO3/c21-16-5-3-14(4-6-16)19(24)2-1-10-22-11-9-15-12-17(23)7-8-18(15)20(25)13-22/h3-8,12,20,23,25H,1-2,9-11,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50331319 ((+/-)-4-(1,7-Dihydroxy-2,3,4,5-tetrahydro-1H-3-ben...) Show SMILES OC1CN(CCCC(=O)c2ccc(F)cc2)CCc2cc(O)ccc12 Show InChI InChI=1S/C20H22FNO3/c21-16-5-3-14(4-6-16)19(24)2-1-10-22-11-9-15-12-17(23)7-8-18(15)20(25)13-22/h3-8,12,20,23,25H,1-2,9-11,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor guinea pig brain after 180 mins scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair