BDBM50331544 7H-furo[3,2-g]chromen-7-one::CHEMBL164660::Furo[3,2-g]chromen-7-one::psoralen

SMILES: O=c1ccc2cc3ccoc3cc2o1

InChI Key: InChIKey=ZCCUUQDIBDJBTK-UHFFFAOYSA-N

Data: 1 KI  8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50331544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2A6 (Homo sapiens (Human))	BDBM50331544 (7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...) Show SMILES O=c1ccc2cc3ccoc3cc2o1 Show InChI InChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Mechanism based inhibition of human cytochrome P450 2A6 measured by coumarin 7-hydroxylation				Curr Drug Metab 6: 413-54 (2005) BindingDB Entry DOI: 10.7270/Q2VQ33X3
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM50331544 (7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...) Show SMILES O=c1ccc2cc3ccoc3cc2o1 Show InChI InChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kinki University Curated by ChEMBL					Assay Description Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK as substrate after 60 mins by fluorescence quenching assay				Bioorg Med Chem 20: 784-8 (2012) Article DOI: 10.1016/j.bmc.2011.12.002 BindingDB Entry DOI: 10.7270/Q2F47PKK
					More data for this Ligand-Target Pair
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human))	BDBM50331544 (7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...) Show SMILES O=c1ccc2cc3ccoc3cc2o1 Show InChI InChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
BioPharmaNet Curated by ChEMBL					Assay Description Inhibition of NF-KB p50 subunit/DNA interaction after 20 mins by EMSA				Bioorg Med Chem 18: 8341-9 (2010) Article DOI: 10.1016/j.bmc.2010.09.063 BindingDB Entry DOI: 10.7270/Q27W6CFD
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50331544 (7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...) Show SMILES O=c1ccc2cc3ccoc3cc2o1 Show InChI InChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sunchon National University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by spectrophotom...				Bioorg Med Chem Lett 29: 839-843 (2019) Article DOI: 10.1016/j.bmcl.2019.01.016
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50331544 (7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...) Show SMILES O=c1ccc2cc3ccoc3cc2o1 Show InChI InChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Monastir Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase (unknown origin) using acetylcholine iodide as substrate preincubated for 15 mins prior to substrate addition by s...				Bioorg Med Chem Lett 23: 4248-52 (2013) Article DOI: 10.1016/j.bmcl.2013.04.081 BindingDB Entry DOI: 10.7270/Q29W0JCX
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50331544 (7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...) Show SMILES O=c1ccc2cc3ccoc3cc2o1 Show InChI InChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sunchon National University Curated by ChEMBL					Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's metho...				Bioorg Med Chem Lett 29: 839-843 (2019) Article DOI: 10.1016/j.bmcl.2019.01.016
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50331544 (7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...) Show SMILES O=c1ccc2cc3ccoc3cc2o1 Show InChI InChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sunchon National University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using benzylamine as substrate after 30 mins by spectrophoto...				Bioorg Med Chem Lett 29: 839-843 (2019) Article DOI: 10.1016/j.bmcl.2019.01.016
					More data for this Ligand-Target Pair
Replicase polyprotein 1a (Human SARS coronavirus (SARS-CoV))	BDBM50331544 (7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...) Show SMILES O=c1ccc2cc3ccoc3cc2o1 Show InChI InChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	8.0	n/a
Gyeongsang National University					Assay Description Reactions were performed in a total volume of 200 mL, which contained thefollowing components: 20mM Tris-buffer, pH 8.0, 10mM DTT, 30 mM Z-RLRGG-AMC,...				J Enzyme Inhib Med Chem 29: 59-63 (2014) Article DOI: 10.3109/14756366.2012.753591 BindingDB Entry DOI: 10.7270/Q21835FQ
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50331544 (7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...) Show SMILES O=c1ccc2cc3ccoc3cc2o1 Show InChI InChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
R.C. Patel Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibition of MAO-A (unknown origin)				Bioorg Med Chem 21: 2434-50 (2013) Article DOI: 10.1016/j.bmc.2013.02.017 BindingDB Entry DOI: 10.7270/Q25T3PCS
					More data for this Ligand-Target Pair