BDBM50331613 CHEMBL1290177::N-(4-chlorobenzyl)benzofuro[2,3-b]pyridin-4-amine

SMILES: Clc1ccc(CNc2ccnc3oc4ccccc4c23)cc1

InChI Key: InChIKey=UAKYYEQJRKJUBT-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50331613 (CHEMBL1290177 | N-(4-chlorobenzyl)benzofuro[2,3-b]...) Show SMILES Clc1ccc(CNc2ccnc3oc4ccccc4c23)cc1 Show InChI InChI=1S/C18H13ClN2O/c19-13-7-5-12(6-8-13)11-21-15-9-10-20-18-17(15)14-3-1-2-4-16(14)22-18/h1-10H,11H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin Luther University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 20: 6915-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.004 BindingDB Entry DOI: 10.7270/Q2GF0TQS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331613 (CHEMBL1290177 | N-(4-chlorobenzyl)benzofuro[2,3-b]...) Show SMILES Clc1ccc(CNc2ccnc3oc4ccccc4c23)cc1 Show InChI InChI=1S/C18H13ClN2O/c19-13-7-5-12(6-8-13)11-21-15-9-10-20-18-17(15)14-3-1-2-4-16(14)22-18/h1-10H,11H2,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin Luther University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 20: 6915-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.004 BindingDB Entry DOI: 10.7270/Q2GF0TQS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50331613 (CHEMBL1290177 | N-(4-chlorobenzyl)benzofuro[2,3-b]...) Show SMILES Clc1ccc(CNc2ccnc3oc4ccccc4c23)cc1 Show InChI InChI=1S/C18H13ClN2O/c19-13-7-5-12(6-8-13)11-21-15-9-10-20-18-17(15)14-3-1-2-4-16(14)22-18/h1-10H,11H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin Luther University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 20: 6915-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.004 BindingDB Entry DOI: 10.7270/Q2GF0TQS
					More data for this Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50331613 (CHEMBL1290177 | N-(4-chlorobenzyl)benzofuro[2,3-b]...) Show SMILES Clc1ccc(CNc2ccnc3oc4ccccc4c23)cc1 Show InChI InChI=1S/C18H13ClN2O/c19-13-7-5-12(6-8-13)11-21-15-9-10-20-18-17(15)14-3-1-2-4-16(14)22-18/h1-10H,11H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin Luther University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of VEGFR3				Bioorg Med Chem Lett 20: 6915-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.004 BindingDB Entry DOI: 10.7270/Q2GF0TQS
					More data for this Ligand-Target Pair