BDBM50331742 2-((R)-9-((R)-1-(4-chlorophenyl)-2-fluoroethyl)-6-fluoro-8-(methylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl)acetic acid::CHEMBL1290639
SMILES: CS(=O)(=O)c1cc(F)cc2c3CCC[C@H](CC(O)=O)c3n([C@@H](CF)c3ccc(Cl)cc3)c12
InChI Key: InChIKey=TYICFEDVTALVHL-KUHUBIRLSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostanoid DP receptor (Homo sapiens (Human)) | BDBM50331742 (2-((R)-9-((R)-1-(4-chlorophenyl)-2-fluoroethyl)-6-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at prostanoid DP1 receptor | Bioorg Med Chem Lett 20: 7462-5 (2010) Article DOI: 10.1016/j.bmcl.2010.10.018 BindingDB Entry DOI: 10.7270/Q2PZ5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50331742 (2-((R)-9-((R)-1-(4-chlorophenyl)-2-fluoroethyl)-6-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at prostanoid TP receptor | Bioorg Med Chem Lett 20: 7462-5 (2010) Article DOI: 10.1016/j.bmcl.2010.10.018 BindingDB Entry DOI: 10.7270/Q2PZ5920 | |||||||||||
More data for this Ligand-Target Pair |