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SMILES: Cc1nnc([nH]1)-c1sccc1NC(=O)Cc1cccc2ccccc12

InChI Key: InChIKey=JIZAXYFIPHHWDF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50332073 (CHEMBL1287974 | N-(2-(5-methyl-1H-1,2,4-triazol-3-...) Show SMILES Cc1nnc([nH]1)-c1sccc1NC(=O)Cc1cccc2ccccc12 Show InChI InChI=1S/C19H16N4OS/c1-12-20-19(23-22-12)18-16(9-10-25-18)21-17(24)11-14-7-4-6-13-5-2-3-8-15(13)14/h2-10H,11H2,1H3,(H,21,24)(H,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant JNK1 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 20: 7303-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.066 BindingDB Entry DOI: 10.7270/Q20865JW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50332073 (CHEMBL1287974 | N-(2-(5-methyl-1H-1,2,4-triazol-3-...) Show SMILES Cc1nnc([nH]1)-c1sccc1NC(=O)Cc1cccc2ccccc12 Show InChI InChI=1S/C19H16N4OS/c1-12-20-19(23-22-12)18-16(9-10-25-18)21-17(24)11-14-7-4-6-13-5-2-3-8-15(13)14/h2-10H,11H2,1H3,(H,21,24)(H,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 20: 7303-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.066 BindingDB Entry DOI: 10.7270/Q20865JW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50332073 (CHEMBL1287974 | N-(2-(5-methyl-1H-1,2,4-triazol-3-...) Show SMILES Cc1nnc([nH]1)-c1sccc1NC(=O)Cc1cccc2ccccc12 Show InChI InChI=1S/C19H16N4OS/c1-12-20-19(23-22-12)18-16(9-10-25-18)21-17(24)11-14-7-4-6-13-5-2-3-8-15(13)14/h2-10H,11H2,1H3,(H,21,24)(H,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant JNK2 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 20: 7303-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.066 BindingDB Entry DOI: 10.7270/Q20865JW
					More data for this Ligand-Target Pair