Found 4 hits for monomerid = 50332085 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM50332085
(CHEMBL1288099 | N-(2-(4H-1,2,4-triazol-3-yl)thioph...)Show InChI InChI=1S/C17H13N5OS/c23-15(9-11-3-1-5-13-12(11)4-2-7-18-13)21-14-6-8-24-16(14)17-19-10-20-22-17/h1-8,10H,9H2,(H,21,23)(H,19,20,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of recombinant JNK1 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 20: 7303-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.066 BindingDB Entry DOI: 10.7270/Q20865JW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50332085
(CHEMBL1288099 | N-(2-(4H-1,2,4-triazol-3-yl)thioph...)Show InChI InChI=1S/C17H13N5OS/c23-15(9-11-3-1-5-13-12(11)4-2-7-18-13)21-14-6-8-24-16(14)17-19-10-20-22-17/h1-8,10H,9H2,(H,21,23)(H,19,20,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of recombinant Erk2 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 20: 7303-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.066 BindingDB Entry DOI: 10.7270/Q20865JW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50332085
(CHEMBL1288099 | N-(2-(4H-1,2,4-triazol-3-yl)thioph...)Show InChI InChI=1S/C17H13N5OS/c23-15(9-11-3-1-5-13-12(11)4-2-7-18-13)21-14-6-8-24-16(14)17-19-10-20-22-17/h1-8,10H,9H2,(H,21,23)(H,19,20,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 20: 7303-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.066 BindingDB Entry DOI: 10.7270/Q20865JW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM50332085
(CHEMBL1288099 | N-(2-(4H-1,2,4-triazol-3-yl)thioph...)Show InChI InChI=1S/C17H13N5OS/c23-15(9-11-3-1-5-13-12(11)4-2-7-18-13)21-14-6-8-24-16(14)17-19-10-20-22-17/h1-8,10H,9H2,(H,21,23)(H,19,20,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of recombinant JNK2 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 20: 7303-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.066 BindingDB Entry DOI: 10.7270/Q20865JW |
More data for this Ligand-Target Pair | |