BDBM50332182 4,3',5'-tri-O-methylpiceatannol::5-(2-(3,5-Dimethoxyphenyl)vinyl)-2-methoxyphenol::5-[(E)-2-(3,5-Dimethoxy-phenyl)-vinyl]-2-methoxy-phenol::5-[2-(3,5-Dimethoxy-phenyl)-vinyl]-2-methoxy-phenol::CHEMBL419378::NSC-381864

SMILES: COc1cc(OC)cc(\C=C\c2ccc(OC)c(O)c2)c1

InChI Key: InChIKey=UQIWTPQGJCCTPA-SNAWJCMRSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50332182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosyldihydronicotinamide dehydrogenase [quinone] (Homo sapiens (Human))	BDBM50332182 (4,3',5'-tri-O-methylpiceatannol | 5-(2-(3,5-Dimeth...) Show SMILES COc1cc(OC)cc(\C=C\c2ccc(OC)c(O)c2)c1 Show InChI InChI=1S/C17H18O4/c1-19-14-8-13(9-15(11-14)20-2)5-4-12-6-7-17(21-3)16(18)10-12/h4-11,18H,1-3H3/b5-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester and Manchester Cancer Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant NQO2				Bioorg Med Chem Lett 20: 7331-6 (2010) Article DOI: 10.1016/j.bmcl.2010.10.070 BindingDB Entry DOI: 10.7270/Q2M32W16
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM50332182 (4,3',5'-tri-O-methylpiceatannol | 5-(2-(3,5-Dimeth...) Show SMILES COc1cc(OC)cc(\C=C\c2ccc(OC)c(O)c2)c1 Show InChI InChI=1S/C17H18O4/c1-19-14-8-13(9-15(11-14)20-2)5-4-12-6-7-17(21-3)16(18)10-12/h4-11,18H,1-3H3/b5-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Campania "L. Vanvitelli" Curated by ChEMBL					Assay Description Inhibition of 5-LOX in human PMNL cells assessed as A23187-stimulated LTB4 production preincubated for 15 mins followed by A23187 addition and measur...				Eur J Med Chem 180: 637-647 (2019) Article DOI: 10.1016/j.ejmech.2019.07.033
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM50332182 (4,3',5'-tri-O-methylpiceatannol | 5-(2-(3,5-Dimeth...) Show SMILES COc1cc(OC)cc(\C=C\c2ccc(OC)c(O)c2)c1 Show InChI InChI=1S/C17H18O4/c1-19-14-8-13(9-15(11-14)20-2)5-4-12-6-7-17(21-3)16(18)10-12/h4-11,18H,1-3H3/b5-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Campania "L. Vanvitelli" Curated by ChEMBL					Assay Description Inhibition of human 5-LOX expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addit...				Eur J Med Chem 180: 637-647 (2019) Article DOI: 10.1016/j.ejmech.2019.07.033
					More data for this Ligand-Target Pair
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human))	BDBM50332182 (4,3',5'-tri-O-methylpiceatannol | 5-(2-(3,5-Dimeth...) Show SMILES COc1cc(OC)cc(\C=C\c2ccc(OC)c(O)c2)c1 Show InChI InChI=1S/C17H18O4/c1-19-14-8-13(9-15(11-14)20-2)5-4-12-6-7-17(21-3)16(18)10-12/h4-11,18H,1-3H3/b5-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester and Manchester Cancer Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant NQO1				Bioorg Med Chem Lett 20: 7331-6 (2010) Article DOI: 10.1016/j.bmcl.2010.10.070 BindingDB Entry DOI: 10.7270/Q2M32W16
					More data for this Ligand-Target Pair