BDBM50332246 (E)-N-(4-Hydroxyphenyl)-6-(4-methoxyphenyl)-4-oxohex-5-enamide::CHEMBL1288118

SMILES: COc1ccc(C=CC(=O)CCC(=O)Nc2ccc(O)cc2)cc1

InChI Key: InChIKey=GWNPSNDHGBCAFF-UHFFFAOYSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50332246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50332246 ((E)-N-(4-Hydroxyphenyl)-6-(4-methoxyphenyl)-4-oxoh...) Show SMILES COc1ccc(C=CC(=O)CCC(=O)Nc2ccc(O)cc2)cc1 |w:6.5| Show InChI InChI=1S/C19H19NO4/c1-24-18-11-3-14(4-12-18)2-7-16(21)10-13-19(23)20-15-5-8-17(22)9-6-15/h2-9,11-12,22H,10,13H2,1H3,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells				Bioorg Med Chem 18: 8463-77 (2010) Article DOI: 10.1016/j.bmc.2010.10.050 BindingDB Entry DOI: 10.7270/Q2319W4V
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50332246 ((E)-N-(4-Hydroxyphenyl)-6-(4-methoxyphenyl)-4-oxoh...) Show SMILES COc1ccc(C=CC(=O)CCC(=O)Nc2ccc(O)cc2)cc1 |w:6.5| Show InChI InChI=1S/C19H19NO4/c1-24-18-11-3-14(4-12-18)2-7-16(21)10-13-19(23)20-15-5-8-17(22)9-6-15/h2-9,11-12,22H,10,13H2,1H3,(H,20,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells				Bioorg Med Chem 18: 8463-77 (2010) Article DOI: 10.1016/j.bmc.2010.10.050 BindingDB Entry DOI: 10.7270/Q2319W4V
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50332246 ((E)-N-(4-Hydroxyphenyl)-6-(4-methoxyphenyl)-4-oxoh...) Show SMILES COc1ccc(C=CC(=O)CCC(=O)Nc2ccc(O)cc2)cc1 |w:6.5| Show InChI InChI=1S/C19H19NO4/c1-24-18-11-3-14(4-12-18)2-7-16(21)10-13-19(23)20-15-5-8-17(22)9-6-15/h2-9,11-12,22H,10,13H2,1H3,(H,20,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells				Bioorg Med Chem 18: 8463-77 (2010) Article DOI: 10.1016/j.bmc.2010.10.050 BindingDB Entry DOI: 10.7270/Q2319W4V
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50332246 ((E)-N-(4-Hydroxyphenyl)-6-(4-methoxyphenyl)-4-oxoh...) Show SMILES COc1ccc(C=CC(=O)CCC(=O)Nc2ccc(O)cc2)cc1 |w:6.5| Show InChI InChI=1S/C19H19NO4/c1-24-18-11-3-14(4-12-18)2-7-16(21)10-13-19(23)20-15-5-8-17(22)9-6-15/h2-9,11-12,22H,10,13H2,1H3,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells				Bioorg Med Chem 18: 8463-77 (2010) Article DOI: 10.1016/j.bmc.2010.10.050 BindingDB Entry DOI: 10.7270/Q2319W4V
					More data for this Ligand-Target Pair