BDBM50332532 (E)-5-(3,4,5-trimethoxybenzylidene)imidazolidine-2,4-dione::CHEMBL1630442

SMILES: COc1cc(\C=C2\NC(=O)NC2=O)cc(OC)c1OC

InChI Key: InChIKey=MIPHJRZSHMVBJB-XBXARRHUSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50332532 ((E)-5-(3,4,5-trimethoxybenzylidene)imidazolidine-2...) Show SMILES COc1cc(\C=C2\NC(=O)NC2=O)cc(OC)c1OC Show InChI InChI=1S/C13H14N2O5/c1-18-9-5-7(6-10(19-2)11(9)20-3)4-8-12(16)15-13(17)14-8/h4-6H,1-3H3,(H2,14,15,16,17)/b8-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
University of Louisiana at Monroe Curated by ChEMBL					Assay Description Inhibition of recombinant GSK3beta Z'-LYTE kinase assay kit method				J Med Chem 53: 8534-45 (2010) Article DOI: 10.1021/jm100941j BindingDB Entry DOI: 10.7270/Q2DB8230
					More data for this Ligand-Target Pair
DNA topoisomerase I (Topo I) (Homo sapiens (Human))	BDBM50332532 ((E)-5-(3,4,5-trimethoxybenzylidene)imidazolidine-2...) Show SMILES COc1cc(\C=C2\NC(=O)NC2=O)cc(OC)c1OC Show InChI InChI=1S/C13H14N2O5/c1-18-9-5-7(6-10(19-2)11(9)20-3)4-8-12(16)15-13(17)14-8/h4-6H,1-3H3,(H2,14,15,16,17)/b8-4+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...				Eur J Med Chem 102: 540-51 (2015) BindingDB Entry DOI: 10.7270/Q2FB54SZ
					More data for this Ligand-Target Pair