BDBM50332947 (S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulfonamido)-N-hydroxyacetamide::CHEMBL1632637

SMILES: COc1ccc(cc1)S(=O)(=O)N(C[C@H](O)CO)CC(=O)NO

InChI Key: InChIKey=FAJZOFHZLDUFEM-VIFPVBQESA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50332947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50332947 ((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(C[C@H](O)CO)CC(=O)NO |r| Show InChI InChI=1S/C12H18N2O7S/c1-21-10-2-4-11(5-3-10)22(19,20)14(6-9(16)8-15)7-12(17)13-18/h2-5,9,15-16,18H,6-8H2,1H3,(H,13,17)/t9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ProtEra s.r.l. Curated by ChEMBL					Assay Description Inhibition of MMP13 by fluorimetric assay				Eur J Med Chem 45: 5919-25 (2010) Article DOI: 10.1016/j.ejmech.2010.09.057 BindingDB Entry DOI: 10.7270/Q29G5N2W
					More data for this Ligand-Target Pair
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50332947 ((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(C[C@H](O)CO)CC(=O)NO |r| Show InChI InChI=1S/C12H18N2O7S/c1-21-10-2-4-11(5-3-10)22(19,20)14(6-9(16)8-15)7-12(17)13-18/h2-5,9,15-16,18H,6-8H2,1H3,(H,13,17)/t9-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ProtEra s.r.l. Curated by ChEMBL					Assay Description Inhibition of MMP12 by fluorimetric assay				Eur J Med Chem 45: 5919-25 (2010) Article DOI: 10.1016/j.ejmech.2010.09.057 BindingDB Entry DOI: 10.7270/Q29G5N2W
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50332947 ((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(C[C@H](O)CO)CC(=O)NO |r| Show InChI InChI=1S/C12H18N2O7S/c1-21-10-2-4-11(5-3-10)22(19,20)14(6-9(16)8-15)7-12(17)13-18/h2-5,9,15-16,18H,6-8H2,1H3,(H,13,17)/t9-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ProtEra s.r.l. Curated by ChEMBL					Assay Description Inhibition of MMP8 by fluorimetric assay				Eur J Med Chem 45: 5919-25 (2010) Article DOI: 10.1016/j.ejmech.2010.09.057 BindingDB Entry DOI: 10.7270/Q29G5N2W
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50332947 ((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(C[C@H](O)CO)CC(=O)NO |r| Show InChI InChI=1S/C12H18N2O7S/c1-21-10-2-4-11(5-3-10)22(19,20)14(6-9(16)8-15)7-12(17)13-18/h2-5,9,15-16,18H,6-8H2,1H3,(H,13,17)/t9-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ProtEra s.r.l. Curated by ChEMBL					Assay Description Inhibition of MMP1 by fluorimetric assay				Eur J Med Chem 45: 5919-25 (2010) Article DOI: 10.1016/j.ejmech.2010.09.057 BindingDB Entry DOI: 10.7270/Q29G5N2W
					More data for this Ligand-Target Pair
Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human))	BDBM50332947 ((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(C[C@H](O)CO)CC(=O)NO |r| Show InChI InChI=1S/C12H18N2O7S/c1-21-10-2-4-11(5-3-10)22(19,20)14(6-9(16)8-15)7-12(17)13-18/h2-5,9,15-16,18H,6-8H2,1H3,(H,13,17)/t9-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ProtEra s.r.l. Curated by ChEMBL					Assay Description Inhibition of MMP7 by fluorimetric assay				Eur J Med Chem 45: 5919-25 (2010) Article DOI: 10.1016/j.ejmech.2010.09.057 BindingDB Entry DOI: 10.7270/Q29G5N2W
					More data for this Ligand-Target Pair