BDBM50333186 (R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-cyclohexylpropanoic acid::CHEMBL1644887

SMILES: OC(=O)[C@@H](CC1CCCCC1)NC(=O)OCC1c2ccccc2-c2ccccc12

InChI Key: InChIKey=HIJAUEZBPWTKIV-JOCHJYFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Deoxyribonuclease gamma (Homo sapiens (Human))	BDBM50333186 ((R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-...) Show SMILES OC(=O)[C@@H](CC1CCCCC1)NC(=O)OCC1c2ccccc2-c2ccccc12 |r| Show InChI InChI=1S/C24H27NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,16,21-22H,1-3,8-9,14-15H2,(H,25,28)(H,26,27)/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Science Curated by ChEMBL					Assay Description Inhibition of human recombinant DNase gamma expressed in Rosetta DE3 cells assessed as increase in acidsoluble DNA after 30 mins				Bioorg Med Chem 19: 168-71 (2011) Article DOI: 10.1016/j.bmc.2010.11.037 BindingDB Entry DOI: 10.7270/Q2PK0GDV
					More data for this Ligand-Target Pair