BDBM50333368 CHEMBL1645348::[11C]-cis-(3-ethyl-2-methylquinolin-6-yl)(4-methoxycyclohexyl)methanone
SMILES: CCc1cc2cc(ccc2nc1C)C(=O)[C@@H]1CC[C@@H](CC1)OC
InChI Key: InChIKey=VEURHZYLLRSEGL-RHNCMZPLSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50333368 (CHEMBL1645348 | [11C]-cis-(3-ethyl-2-methylquinoli...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Radiological Sciences Curated by ChEMBL | Assay Description Binding affinity to mGluR1 by PET analysis | Bioorg Med Chem Lett 21: 2998-3001 (2011) Article DOI: 10.1016/j.bmcl.2011.03.046 BindingDB Entry DOI: 10.7270/Q2WH2Q9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50333368 (CHEMBL1645348 | [11C]-cis-(3-ethyl-2-methylquinoli...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Radiological Sciences Curated by ChEMBL | Assay Description Binding affinity to mGluR1 | Bioorg Med Chem 19: 102-10 (2011) Article DOI: 10.1016/j.bmc.2010.11.048 BindingDB Entry DOI: 10.7270/Q21R6QSS | |||||||||||
More data for this Ligand-Target Pair |