BDBM50333416 7-(2-Methoxyethoxy)-1-methyl-beta-carboline::CHEMBL1645546::US9168247, JR220

SMILES: COCCOc1ccc2c(c1)[nH]c1c(C)nccc21

InChI Key: InChIKey=HSBQAAURJDHACO-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50333416 (7-(2-Methoxyethoxy)-1-methyl-beta-carboline | CHEM...) Show SMILES COCCOc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C15H16N2O2/c1-10-15-13(5-6-16-10)12-4-3-11(9-14(12)17-15)19-8-7-18-2/h3-6,9,17H,7-8H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Facult£s Universitaires Notre-Dame de la Paix Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...				Bioorg Med Chem 19: 134-44 (2011) Article DOI: 10.1016/j.bmc.2010.11.041 BindingDB Entry DOI: 10.7270/Q2NK3F9X
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50333416 (7-(2-Methoxyethoxy)-1-methyl-beta-carboline | CHEM...) Show SMILES COCCOc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C15H16N2O2/c1-10-15-13(5-6-16-10)12-4-3-11(9-14(12)17-15)19-8-7-18-2/h3-6,9,17H,7-8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur (FUNDP) Curated by ChEMBL					Assay Description Inhibition of DYRK1A kinase using RBER-CHKtide substrate by radiometric protein kinase assay				J Med Chem 55: 6489-501 (2012) Article DOI: 10.1021/jm300542e BindingDB Entry DOI: 10.7270/Q2GM88FB
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50333416 (7-(2-Methoxyethoxy)-1-methyl-beta-carboline | CHEM...) Show SMILES COCCOc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C15H16N2O2/c1-10-15-13(5-6-16-10)12-4-3-11(9-14(12)17-15)19-8-7-18-2/h3-6,9,17H,7-8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	7.5	n/a
FACULTES UNIVERSITAIRES NOTRE DAME DE LA PAIX; UNIVERSITE LIBRE BRUXELLES US Patent					Assay Description A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of DYRK1A protein kinase. All kinase assay...				US Patent US9168247 (2015) BindingDB Entry DOI: 10.7270/Q2X63KQN
					More data for this Ligand-Target Pair