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SMILES: Cc1ccc(NC(=O)C(Cc2ccc(O)cc2)NC(=O)c2ccccc2N)cc1

InChI Key: InChIKey=JSAOIYNBSQMJDT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333664   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50333664
PNG
(2-amino-N-(3-(4-hydroxyphenyl)-1-oxo-1-(p-tolylami...)
Show SMILES Cc1ccc(NC(=O)C(Cc2ccc(O)cc2)NC(=O)c2ccccc2N)cc1
Show InChI InChI=1S/C23H23N3O3/c1-15-6-10-17(11-7-15)25-23(29)21(14-16-8-12-18(27)13-9-16)26-22(28)19-4-2-3-5-20(19)24/h2-13,21,27H,14,24H2,1H3,(H,25,29)(H,26,28)
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Similars
Article
PubMed
n/an/a 1.19E+4n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged Aurora A kinase expressed in insect cells

Bioorg Med Chem 19: 907-16 (2011)


Article DOI: 10.1016/j.bmc.2010.11.064
BindingDB Entry DOI: 10.7270/Q2V40VGC
More data for this
Ligand-Target Pair