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SMILES: COc1ccc2sc(SCC(=O)Nc3ncc(Br)s3)nc2c1

InChI Key: InChIKey=TVLYUBGSMNMTKB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333667   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50333667
PNG
(CHEMBL1643148 | N-(5-bromothiazol-2-yl)-2-(5-metho...)
Show SMILES COc1ccc2sc(SCC(=O)Nc3ncc(Br)s3)nc2c1
Show InChI InChI=1S/C13H10BrN3O2S3/c1-19-7-2-3-9-8(4-7)16-13(21-9)20-6-11(18)17-12-15-5-10(14)22-12/h2-5H,6H2,1H3,(H,15,17,18)
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PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged Aurora A kinase expressed in insect cells

Bioorg Med Chem 19: 907-16 (2011)


Article DOI: 10.1016/j.bmc.2010.11.064
BindingDB Entry DOI: 10.7270/Q2V40VGC
More data for this
Ligand-Target Pair