BDBM50333717 2-(2-(3,5-dimethylphenyl)-1-(2-hydroxypropyl)-1H-indol-5-yl)-N,N,2-trimethylpropanamide::CHEMBL1643714

SMILES: CC(O)Cn1c(cc2cc(ccc12)C(C)(C)C(=O)N(C)C)-c1cc(C)cc(C)c1

InChI Key: InChIKey=DSFRUNSNUAICKP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated calcium channel subunit alpha Cav2.2 (Homo sapiens (Human))	BDBM50333717 (2-(2-(3,5-dimethylphenyl)-1-(2-hydroxypropyl)-1H-i...) Show SMILES CC(O)Cn1c(cc2cc(ccc12)C(C)(C)C(=O)N(C)C)-c1cc(C)cc(C)c1 Show InChI InChI=1S/C25H32N2O2/c1-16-10-17(2)12-19(11-16)23-14-20-13-21(25(4,5)24(29)26(6)7)8-9-22(20)27(23)15-18(3)28/h8-14,18,28H,15H2,1-7H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Blockade of Cav2.2 channel by fluorescent calcium-influx assay				Bioorg Med Chem Lett 21: 869-73 (2011) Article DOI: 10.1016/j.bmcl.2010.11.067 BindingDB Entry DOI: 10.7270/Q2B27VJK
					More data for this Ligand-Target Pair