BDBM50333851 (R)-2-(7-(4-fluoro-N-(2,2,2-trifluoroethyl)phenylsulfonamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid::CHEMBL1643790

SMILES: OC(=O)Cc1c2CC[C@H](Cn2c2ccccc12)N(CC(F)(F)F)S(=O)(=O)c1ccc(F)cc1

InChI Key: InChIKey=OELVPGVSMLPSGD-OAHLLOKOSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333851   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50333851 ((R)-2-(7-(4-fluoro-N-(2,2,2-trifluoroethyl)phenyls...) Show SMILES OC(=O)Cc1c2CC[C@H](Cn2c2ccccc12)N(CC(F)(F)F)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C22H20F4N2O4S/c23-14-5-8-16(9-6-14)33(31,32)28(13-22(24,25)26)15-7-10-20-18(11-21(29)30)17-3-1-2-4-19(17)27(20)12-15/h1-6,8-9,15H,7,10-13H2,(H,29,30)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assay				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50333851 ((R)-2-(7-(4-fluoro-N-(2,2,2-trifluoroethyl)phenyls...) Show SMILES OC(=O)Cc1c2CC[C@H](Cn2c2ccccc12)N(CC(F)(F)F)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C22H20F4N2O4S/c23-14-5-8-16(9-6-14)33(31,32)28(13-22(24,25)26)15-7-10-20-18(11-21(29)30)17-3-1-2-4-19(17)27(20)12-15/h1-6,8-9,15H,7,10-13H2,(H,29,30)/t15-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to prostanoid DP1 receptor				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50333851 ((R)-2-(7-(4-fluoro-N-(2,2,2-trifluoroethyl)phenyls...) Show SMILES OC(=O)Cc1c2CC[C@H](Cn2c2ccccc12)N(CC(F)(F)F)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C22H20F4N2O4S/c23-14-5-8-16(9-6-14)33(31,32)28(13-22(24,25)26)15-7-10-20-18(11-21(29)30)17-3-1-2-4-19(17)27(20)12-15/h1-6,8-9,15H,7,10-13H2,(H,29,30)/t15-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to thromboxane receptor				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50333851 ((R)-2-(7-(4-fluoro-N-(2,2,2-trifluoroethyl)phenyls...) Show SMILES OC(=O)Cc1c2CC[C@H](Cn2c2ccccc12)N(CC(F)(F)F)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C22H20F4N2O4S/c23-14-5-8-16(9-6-14)33(31,32)28(13-22(24,25)26)15-7-10-20-18(11-21(29)30)17-3-1-2-4-19(17)27(20)12-15/h1-6,8-9,15H,7,10-13H2,(H,29,30)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRTH2 receptor expressed in HEK293 cells assessed as inhibition of DK-PGD2-induced intracellular cAMP format...				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair