BDBM50333860 (R)-2-(7-(1-(4-fluorophenyl)-N-methylmethylsulfonamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid::CHEMBL1643800

SMILES: CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)S(=O)(=O)Cc1ccc(F)cc1

InChI Key: InChIKey=GKCUCOILFCQCEO-QGZVFWFLSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50333860 ((R)-2-(7-(1-(4-fluorophenyl)-N-methylmethylsulfona...) Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)S(=O)(=O)Cc1ccc(F)cc1 |r| Show InChI InChI=1S/C22H23FN2O4S/c1-24(30(28,29)14-15-6-8-16(23)9-7-15)17-10-11-21-19(12-22(26)27)18-4-2-3-5-20(18)25(21)13-17/h2-9,17H,10-14H2,1H3,(H,26,27)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assay				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50333860 ((R)-2-(7-(1-(4-fluorophenyl)-N-methylmethylsulfona...) Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)S(=O)(=O)Cc1ccc(F)cc1 |r| Show InChI InChI=1S/C22H23FN2O4S/c1-24(30(28,29)14-15-6-8-16(23)9-7-15)17-10-11-21-19(12-22(26)27)18-4-2-3-5-20(18)25(21)13-17/h2-9,17H,10-14H2,1H3,(H,26,27)/t17-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	799	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to prostanoid DP1 receptor				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50333860 ((R)-2-(7-(1-(4-fluorophenyl)-N-methylmethylsulfona...) Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)S(=O)(=O)Cc1ccc(F)cc1 |r| Show InChI InChI=1S/C22H23FN2O4S/c1-24(30(28,29)14-15-6-8-16(23)9-7-15)17-10-11-21-19(12-22(26)27)18-4-2-3-5-20(18)25(21)13-17/h2-9,17H,10-14H2,1H3,(H,26,27)/t17-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to thromboxane receptor				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50333860 ((R)-2-(7-(1-(4-fluorophenyl)-N-methylmethylsulfona...) Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)S(=O)(=O)Cc1ccc(F)cc1 |r| Show InChI InChI=1S/C22H23FN2O4S/c1-24(30(28,29)14-15-6-8-16(23)9-7-15)17-10-11-21-19(12-22(26)27)18-4-2-3-5-20(18)25(21)13-17/h2-9,17H,10-14H2,1H3,(H,26,27)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRTH2 receptor expressed in HEK293 cells assessed as inhibition of DK-PGD2-induced intracellular cAMP format...				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair