BDBM50333929 CHEMBL1644418::[(2R,6R,10S,15S,17R)-13-benzyl-6-hydroxy-4,17-dimethyl-5-oxo-15-(prop-1-en-2-yl)-12,14,18-trioxapentacyclo[11.4.1.0^{1,10}.0^{2,6}.0^{11,15}]octadeca-3,8-dien-8-yl]methyl 2-(3,5-dibromophenyl)acetate

SMILES: C[C@@H]1C[C@]2(OC3(Cc4ccccc4)OC2[C@@H]2C=C(COC(=O)Cc4cc(Br)cc(Br)c4)C[C@@]4(O)[C@@H](C=C(C)C4=O)C12O3)C(C)=C

InChI Key: InChIKey=HIDNRZRSVUEPIG-JPOOWHRWSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50333929 (CHEMBL1644418 | [(2R,6R,10S,15S,17R)-13-benzyl-6-h...) Show SMILES C[C@@H]1C[C@]2(OC3(Cc4ccccc4)OC2[C@@H]2C=C(COC(=O)Cc4cc(Br)cc(Br)c4)C[C@@]4(O)[C@@H](C=C(C)C4=O)C12O3)C(C)=C |r,t:18,38,TLB:4:5:15:3.2.1,42:3:15:41.13.5,THB:4:3:15:41.13.5,0:1:15:41.13.5| Show InChI InChI=1S/C36H36Br2O7/c1-20(2)34-16-22(4)36-28(32(34)43-35(44-34,45-36)18-23-8-6-5-7-9-23)13-25(17-33(41)29(36)10-21(3)31(33)40)19-42-30(39)14-24-11-26(37)15-27(38)12-24/h5-13,15,22,28-29,32,41H,1,14,16-19H2,2-4H3/t22-,28+,29-,32?,33-,34+,35?,36?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from rat TRV1 expressed in CHO cells by competitive binding assay				Bioorg Med Chem Lett 21: 299-302 (2010) Article DOI: 10.1016/j.bmcl.2010.11.012 BindingDB Entry DOI: 10.7270/Q2J967BB
					More data for this Ligand-Target Pair
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50333929 (CHEMBL1644418 | [(2R,6R,10S,15S,17R)-13-benzyl-6-h...) Show SMILES C[C@@H]1C[C@]2(OC3(Cc4ccccc4)OC2[C@@H]2C=C(COC(=O)Cc4cc(Br)cc(Br)c4)C[C@@]4(O)[C@@H](C=C(C)C4=O)C12O3)C(C)=C |r,t:18,38,TLB:4:5:15:3.2.1,42:3:15:41.13.5,THB:4:3:15:41.13.5,0:1:15:41.13.5| Show InChI InChI=1S/C36H36Br2O7/c1-20(2)34-16-22(4)36-28(32(34)43-35(44-34,45-36)18-23-8-6-5-7-9-23)13-25(17-33(41)29(36)10-21(3)31(33)40)19-42-30(39)14-24-11-26(37)15-27(38)12-24/h5-13,15,22,28-29,32,41H,1,14,16-19H2,2-4H3/t22-,28+,29-,32?,33-,34+,35?,36?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at rat TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake				Bioorg Med Chem Lett 21: 299-302 (2010) Article DOI: 10.1016/j.bmcl.2010.11.012 BindingDB Entry DOI: 10.7270/Q2J967BB
					More data for this Ligand-Target Pair