Found 4 hits for monomerid = 50333952 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50333952
(CHEMBL1644470 | exo-(1R,5S)-3-(6-phenylpyridin-2-y...)Show SMILES C1C[C@@H]2C[C@H](C[C@H]1N2)Oc1cccc(n1)-c1ccccc1 |r| Show InChI InChI=1S/C18H20N2O/c1-2-5-13(6-3-1)17-7-4-8-18(20-17)21-16-11-14-9-10-15(12-16)19-14/h1-8,14-16,19H,9-12H2/t14-,15+,16- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
MSD
Curated by ChEMBL
| Assay Description Inhibition of human ERG by dofetilide binding assay |
Bioorg Med Chem Lett 21: 271-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50333952
(CHEMBL1644470 | exo-(1R,5S)-3-(6-phenylpyridin-2-y...)Show SMILES C1C[C@@H]2C[C@H](C[C@H]1N2)Oc1cccc(n1)-c1ccccc1 |r| Show InChI InChI=1S/C18H20N2O/c1-2-5-13(6-3-1)17-7-4-8-18(20-17)21-16-11-14-9-10-15(12-16)19-14/h1-8,14-16,19H,9-12H2/t14-,15+,16- | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
MSD
Curated by ChEMBL
| Assay Description Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation counting |
Bioorg Med Chem Lett 21: 271-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333952
(CHEMBL1644470 | exo-(1R,5S)-3-(6-phenylpyridin-2-y...)Show SMILES C1C[C@@H]2C[C@H](C[C@H]1N2)Oc1cccc(n1)-c1ccccc1 |r| Show InChI InChI=1S/C18H20N2O/c1-2-5-13(6-3-1)17-7-4-8-18(20-17)21-16-11-14-9-10-15(12-16)19-14/h1-8,14-16,19H,9-12H2/t14-,15+,16- | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
MSD
Curated by ChEMBL
| Assay Description Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation counting |
Bioorg Med Chem Lett 21: 271-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50333952
(CHEMBL1644470 | exo-(1R,5S)-3-(6-phenylpyridin-2-y...)Show SMILES C1C[C@@H]2C[C@H](C[C@H]1N2)Oc1cccc(n1)-c1ccccc1 |r| Show InChI InChI=1S/C18H20N2O/c1-2-5-13(6-3-1)17-7-4-8-18(20-17)21-16-11-14-9-10-15(12-16)19-14/h1-8,14-16,19H,9-12H2/t14-,15+,16- | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MSD
Curated by ChEMBL
| Assay Description Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation counting |
Bioorg Med Chem Lett 21: 271-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3 |
More data for this Ligand-Target Pair | |