BDBM50334148 (S)-4-(1-(5-(trifluoromethyl)-1-(4-(trifluoromethyl)benzyl)indoline-7-carboxamido)ethyl)benzoic acid::CHEMBL1645154

SMILES: C[C@H](NC(=O)c1cc(cc2CCN(Cc3ccc(cc3)C(F)(F)F)c12)C(F)(F)F)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=KUCXVWMJDTUHKY-HNNXBMFYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50334148 ((S)-4-(1-(5-(trifluoromethyl)-1-(4-(trifluoromethy...) Show SMILES C[C@H](NC(=O)c1cc(cc2CCN(Cc3ccc(cc3)C(F)(F)F)c12)C(F)(F)F)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C27H22F6N2O3/c1-15(17-4-6-18(7-5-17)25(37)38)34-24(36)22-13-21(27(31,32)33)12-19-10-11-35(23(19)22)14-16-2-8-20(9-3-16)26(28,29)30/h2-9,12-13,15H,10-11,14H2,1H3,(H,34,36)(H,37,38)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 21: 484-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.106 BindingDB Entry DOI: 10.7270/Q2BZ6695
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50334148 ((S)-4-(1-(5-(trifluoromethyl)-1-(4-(trifluoromethy...) Show SMILES C[C@H](NC(=O)c1cc(cc2CCN(Cc3ccc(cc3)C(F)(F)F)c12)C(F)(F)F)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C27H22F6N2O3/c1-15(17-4-6-18(7-5-17)25(37)38)34-24(36)22-13-21(27(31,32)33)12-19-10-11-35(23(19)22)14-16-2-8-20(9-3-16)26(28,29)30/h2-9,12-13,15H,10-11,14H2,1H3,(H,34,36)(H,37,38)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Inc. Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 21: 484-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.106 BindingDB Entry DOI: 10.7270/Q2BZ6695
					More data for this Ligand-Target Pair