BDBM50334161 1'-(4-fluorobenzyl)-3-(2-fluoroethyl)-3H-spiro[isobenzofuran-1,4'-piperidine]::CHEMBL1645205
SMILES: FCCC1OC2(CCN(Cc3ccc(F)cc3)CC2)c2ccccc12
InChI Key: InChIKey=VMHRVUVGXYYBON-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig)) | BDBM50334161 (1'-(4-fluorobenzyl)-3-(2-fluoroethyl)-3H-spiro[iso...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL | Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane by scintillation counting | Bioorg Med Chem 19: 393-405 (2011) Article DOI: 10.1016/j.bmc.2010.11.013 BindingDB Entry DOI: 10.7270/Q23F4PWG | |||||||||||
More data for this Ligand-Target Pair |