BDBM50334228 CHEMBL1641998::N-(1-(3-Bromophenylamino)-4-cyanoisoquinolin-7-yl)-3-(1H-indol-3-yl)propanamide

SMILES: Brc1cccc(Nc2ncc(C#N)c3ccc(NC(=O)CCc4cc5ccccc5[nH]4)cc23)c1

InChI Key: InChIKey=XQAGTHUVMXMRDQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50334228 (CHEMBL1641998 | N-(1-(3-Bromophenylamino)-4-cyanoi...) Show SMILES Brc1cccc(Nc2ncc(C#N)c3ccc(NC(=O)CCc4cc5ccccc5[nH]4)cc23)c1 Show InChI InChI=1S/C27H20BrN5O/c28-19-5-3-6-20(13-19)33-27-24-14-22(8-10-23(24)18(15-29)16-30-27)32-26(34)11-9-21-12-17-4-1-2-7-25(17)31-21/h1-8,10,12-14,16,31H,9,11H2,(H,30,33)(H,32,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Genomics Centre of the Max Planck Society Curated by ChEMBL					Assay Description Inhibition of EGFR by HTRF assay				Bioorg Med Chem 19: 429-39 (2011) Article DOI: 10.1016/j.bmc.2010.11.007 BindingDB Entry DOI: 10.7270/Q22F7NQN
					More data for this Ligand-Target Pair