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SMILES: FC1(F)CCC(CC1)NC(=O)C(C1CCCCC1)n1c(nc2ccccc12)-c1ccc(Cl)cc1

InChI Key: InChIKey=XLQNAXOTPQZOIM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334241   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bile acid receptor


(Homo sapiens (Human))		BDBM50334241
PNG
(2-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)-2-...)
Show SMILES FC1(F)CCC(CC1)NC(=O)C(C1CCCCC1)n1c(nc2ccccc12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C27H30ClF2N3O/c28-20-12-10-19(11-13-20)25-32-22-8-4-5-9-23(22)33(25)24(18-6-2-1-3-7-18)26(34)31-21-14-16-27(29,30)17-15-21/h4-5,8-13,18,21,24H,1-3,6-7,14-17H2,(H,31,34)
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Similars
Article
PubMed
n/an/a 2.72E+3n/an/an/an/an/an/a



F Hoffmann-La Roche AG

Curated by ChEMBL


Assay Description
Displacement of radioligand from human FXR by scintillation proximity assay

Bioorg Med Chem Lett 21: 191-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.11.039
BindingDB Entry DOI: 10.7270/Q2XP757R
More data for this
Ligand-Target Pair