BDBM50334470 1,12-bis(3,4-dihydroisoquinolin-2(1H)-yl)dodecane::CHEMBL1643946

SMILES: C(CCCCCCN1CCc2ccccc2C1)CCCCCN1CCc2ccccc2C1

InChI Key: InChIKey=NUISVTXFABNDON-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-6 subunit (Rattus norvegicus)	BDBM50334470 (1,12-bis(3,4-dihydroisoquinolin-2(1H)-yl)dodecane ...) Show SMILES C(CCCCCCN1CCc2ccccc2C1)CCCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C30H44N2/c1(3-5-7-13-21-31-23-19-27-15-9-11-17-29(27)25-31)2-4-6-8-14-22-32-24-20-28-16-10-12-18-30(28)26-32/h9-12,15-18H,1-8,13-14,19-26H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.59	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine release				Bioorg Med Chem Lett 21: 88-91 (2010) Article DOI: 10.1016/j.bmcl.2010.11.070 BindingDB Entry DOI: 10.7270/Q2VT1SDX
					More data for this Ligand-Target Pair