BDBM50334471 1,10-bis(3,4-dihydroisoquinolin-2(1H)-yl)decane::CHEMBL1643947

SMILES: C(CCCCCN1CCc2ccccc2C1)CCCCN1CCc2ccccc2C1

InChI Key: InChIKey=VJWBVWNQBLXWOM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-6 subunit (Rattus norvegicus)	BDBM50334471 (1,10-bis(3,4-dihydroisoquinolin-2(1H)-yl)decane | ...) Show SMILES C(CCCCCN1CCc2ccccc2C1)CCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C28H40N2/c1(3-5-11-19-29-21-17-25-13-7-9-15-27(25)23-29)2-4-6-12-20-30-22-18-26-14-8-10-16-28(26)24-30/h7-10,13-16H,1-6,11-12,17-24H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.91	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine release				Bioorg Med Chem Lett 21: 88-91 (2010) Article DOI: 10.1016/j.bmcl.2010.11.070 BindingDB Entry DOI: 10.7270/Q2VT1SDX
					More data for this Ligand-Target Pair